MRS2693 trisodium
MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM. MRS2693 trisodium can reduce the activation of NF-kappaB and activate the ERK1/2 pathway, and has a cytoprotective effect on mouse hindlimb skeletal muscle ischemia-reperfusion injury model.
For research use only. We do not sell to patients.
- CAS No.: 1448858-83-0
- Formula: C9H10IN2Na3O12P2
- Molecular Weight:596.00
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-W010832
Uridine-5'-diphosphate disodium saltNucleotide -
HY-10064
TicagrelorP2Y12 Antagonist -
HY-W010832R
Uridine-5'-diphosphate disodium salt (Standard)Reference Standard -
HY-108648
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HY-15284A
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HY-108656
MRS2365P2Y1 receptor/[35S]GTPγS binding/β-arrestin 2 recruitment Agonist -
HY-108654
PSB 0474P2Y6 Receptor Agonist -
HY-108658
MRS2500 tetraammoniumP2Y1 Receptor Antagonist -
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AZD1283P2Y12 Receptor Antagonist -
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PITP2Y1 Receptor Antagonist -
HY-117356A
MRS2693 ammoniumP2Y6R Activator
All P2Y Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 1448858-83-0
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Appearance Liquid
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Molecular Weight 596.00
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Formula C9H10IN2Na3O12P2
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Color Colorless to light yellow
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Girard M, et al. Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor. Biochim Biophys Acta Mol Cell Res. 2023 Jun;1870(5):119476. [Content Brief]
[2]. Mamedova LK, et al. Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol Res. 2008 Sep-Oct;58(3-4):232-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRS2693 trisodium Related Classifications
HY-117356B Related Classifications
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