N-Acetylciprofloxacin
Based on 1 Customer Validation
N-Acetylciprofloxacin is the metabolite of Ciprofloxacin (HY-B0356).
For research use only. We do not sell to patients.
- Purity : 99.53%
- CAS No.: 93594-20-8
- Formula: C19H20FN3O4
- Molecular Weight:373.38
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Storage:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
584 μM
Compound: 6a
|
Antitumor activity against human A549 cells after 5 days by MTT assay
Antitumor activity against human A549 cells after 5 days by MTT assay
|
[PMID: 19595598] |
| LoVo | IC50 |
323 μM
Compound: 6a
|
Antitumor activity against human LoVo cells after 5 days by MTT assay
Antitumor activity against human LoVo cells after 5 days by MTT assay
|
[PMID: 19595598] |
| MCF7 | IC50 |
803 μM
Compound: 6a
|
Antitumor activity against human MCF7 cells after 5 days by MTT assay
Antitumor activity against human MCF7 cells after 5 days by MTT assay
|
[PMID: 19595598] |
| PC-3 | IC50 |
680 μM
Compound: 6a
|
Antitumor activity against human PC3 cells after 5 days by MTT assay
Antitumor activity against human PC3 cells after 5 days by MTT assay
|
[PMID: 19595598] |
| U-373MG ATCC | IC50 |
535 μM
Compound: 6a
|
Antitumor activity against human U373MG cells after 5 days by MTT assay
Antitumor activity against human U373MG cells after 5 days by MTT assay
|
[PMID: 19595598] |
Chemical Information
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CAS No. 93594-20-8
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Appearance Solid
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Molecular Weight 373.38
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Formula C19H20FN3O4
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Color White to off-white
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SMILES
O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(C(C)=O)CC4)=C3)C1=O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 5 mg/mL (13.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6782 mL | 13.3912 mL | 26.7824 mL | 66.9559 mL |
| 5 mM | 0.5356 mL | 2.6782 mL | 5.3565 mL | 13.3912 mL | |
| 10 mM | 0.2678 mL | 1.3391 mL | 2.6782 mL | 6.6956 mL |