NAMPT ligand-1
NAMPT ligand-1 is a ligand targeting NAMPT, consisting of a NAMPT-binding domain, a linker, and a maleimide-fused enediyne warhead with a cyclopropane-modified alkyne terminus. NAMPT ligand-1 can be used to synthesize PROTEC NAMPT Degrader-1 (HY-189001). NAMPT ligand-1 induces the degradation of NAMPT via proximity-induced radical oxidation, and this process is independent of endogenous proteolytic mechanisms. NAMPT ligand-1 can be used in ovarian cancer research.
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- 分子式: C30H41NO4
- 分子量:479.65
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
化学情報
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分子量 479.65
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分子式 C30H41NO4
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SMILES
O=C(O)CCCCCN1C(C(C#CC(C2CC2)CCCC)=C(C#CC(C3CC3)CCCC)C1=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
NAMPT ligand-1 関連分類
HY-188123 関連分類
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Keywords
- NAMPT ligand-1
- NAMPT ligand1
- NAMPT ligand 1
- PROTECs
- NAMPT
- Protein-Radical-Oxidation Targeting Enediyne Chimera
- Nicotinamide phosphoribosyl transferase
- PBEF
- Visfatin
- pre-B cell-enhancing factor
- Pre-B cell colony enhancing factor
- maleimide-fused enediyne warhead
- NAMPT-binding moiety
- cyclopropane-modified alkyne terminus
- ovarian cancer
- Inhibitor
- inhibitor
- inhibit