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Cat. No.: HY-125362

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Nannochelin C

Nannochelin C is a citrate-hydroxamate siderophore and iron chelator found in Nannocystis exedens strain Na e485. The MIC of Nannochelin C against Brevibacterium ammoniagenes is 0.39 μg/mL, and it exhibits weak growth inhibitory activity against some Gram-positive bacteria. The antimicrobial effect of Nannochelin C may be associated with its metal chelating activity. Nannochelin C can be used in studies related to siderophores, microbial iron metabolism and antimicrobial activity.

For research use only. We do not sell to patients.

CAS No.: 133705-26-7
Formula: C₃₆H₄₄N₄O₁₃
Molecular Weight:740.75

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Please store the product under the recommended conditions in the Certificate of Analysis.

Nannochelin C Chemical Structure

CAS No.: 133705-26-7

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Nannochelin C (40 μg/disc) exhibits weak antibacterial activity against some Gram-positive bacteria in the agar diffusion assay, with inhibition zone diameters of 15 mm and 22 mm against Bacillus megaterium and Brevibacterium ammoniagenes, respectively^[1].
Nannochelin C inhibits the growth of *Brevibacterium ammoniagenes* with an MIC of 0.39 μg/mL^[1].
Nannochelin C (40 μg/disc) exhibits incomplete inhibition against Micrococcus luteus, Staphylococcus aureus, and Rhizopus arrhizus, with inhibition zone diameters of 14, 16, and 15 mm, respectively, but shows no detectable growth inhibition against Escherichia coli, Salmonella typhimurium, and Candida albicans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 133705-26-7
Molecular Weight 740.75
Formula C₃₆H₄₄N₄O₁₃
SMILES

O=C(/C=C/C1=CC=CC=C1)N(O)CCCC[C@@H](C(O)=O)NC(CC(C(O)=O)(O)CC(N[C@H](C(O)=O)CCCCN(O)C(/C=C/C2=CC=CC=C2)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kunze B, et al. Nannochelins A, B and C, new iron-chelating compounds from Nannocystis exedens (Myxobacteria). Production, isolation, physico-chemical and biological properties. J Antibiot. 1992;45(2):147-150. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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