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Cat. No.: HY-181615

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Nav1.8-IN-22

Nav1.8-IN-22 (Formula I) is a Nav1.8 sodium channel inhibitor. Nav1.8-IN-22 regulates sodium channel activity by directly binding to Nav1.8. Nav1.8-IN-22 is applicable for pain-related research.

For research use only. We do not sell to patients.

CAS No.: 2966089-13-2
Formula: C₂₁H₂₁F₂N₅O₃S
Molecular Weight:461.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nav1.8-IN-22 Chemical Structure

CAS No.: 2966089-13-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

Na_v1.8

All Sodium Channel Isoforms :

Chemical Information

CAS No. 2966089-13-2
Molecular Weight 461.48
Formula C₂₁H₂₁F₂N₅O₃S
SMILES

NS(=O)(C1=NC=CC(NC(C2=CC3=CC=CC=C3N=C2N4CCCC(F)(CC4)F)=O)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ke Xiao, et al. Crystal forms of aromatic fused-ring nav1.8 inhibitor and salt thereof, pharmaceutical composition, and use. WO2026021410A1.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Nav1.8-IN-22

All Sodium Channel Isoforms