NHS-PEG-NHS
Based on 1 Customer Validation
NHS-PEG-NHS is a derivative of activated polyethylene glycol (PEG) that can modify functional groups on protein surfaces via covalent binding. NHS-PEG-NHS serves as a bioconjugation modification reagent for modifying proteins, enzymes, peptides and antibodies.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- CAS No.: 122375-06-8
- Formula: (C2H4O)nC10H8N2O9
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NHS-PEG-NHS (Compound 13) (24-72 h) shows an activation rate of 88% and polydispersity of 1.03 in vitro assays, indicating stable covalent binding to protein functional groups, and demonstrates selective PEGylation efficiency in protein modification experiments, reducing immunogenicity and prolonging biomolecule half-life[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 122375-06-8
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Appearance Solid
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Formula (C2H4O)nC10H8N2O9
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SMILES
O=C(OCCOC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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