Nicousamide
Nicousamide is a potent inhibitor of TGF-β RII phosphorylation. Nicousamide can be used to study renal fibrosis in animal models of diabetic nephropathy.
For research use only. We do not sell to patients.
- CAS No.: 704881-43-6
- Formula: C18H12N2O9
- Molecular Weight:400.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
>312 μM
Compound: DW-3
|
Cytotoxicity against mock-infected human MT4 cells assessed as reduction in cell viability measured after 5 days by MTT assay
Cytotoxicity against mock-infected human MT4 cells assessed as reduction in cell viability measured after 5 days by MTT assay
|
[PMID: 34403976] |
Chemical Information
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CAS No. 704881-43-6
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Molecular Weight 400.30
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Formula C18H12N2O9
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SMILES
O=C(C1=CC(NC(C2=CC3=CC([N+]([O-])=O)=C(C(C)=C3OC2=O)O)=O)=CC=C1O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)