CC13401
CC13401 is an aldose reductase (ALR2) inhibitor with an IC50 of 41.41 μM in rats. CC13401 inhibits the NADPH-dependent reduction reaction catalyzed by ALR2. CC13401 can be used in studies on the mechanisms related to the polyol pathway and diabetic complications.
For research use only. We do not sell to patients.
- CAS No.: 158575-73-6
- Formula: C17H15NO4
- Molecular Weight:297.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
ALR2 41.41 μM (IC50) |
In Vitro
CC13401 (compound 9) tested as a racemate, specifically inhibits rat lens-derived aldose reductase with an IC50 of 41.41 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 158575-73-6
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Molecular Weight 297.31
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Formula C17H15NO4
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SMILES
O=C(N1C2=CC=CC=C2C[C@@H]1C(O)=O)OCC3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CC13401 Related Classifications
HY-187119 Related Classifications
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