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Cat. No.: HY-176505

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NOP antagonist 1

NOP antagonist 1 (Compound (-)-31) is a nociceptin opioid peptide (NOP) antagonist with a K_b of 8.65  nM. NOP antagonist 1 can be used for neuropsychiatric disorders research.

For research use only. We do not sell to patients.

CAS No.: 1283095-64-6
Formula: C₂₁H₂₄F₂N₂O₂S
Molecular Weight:406.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

NOP antagonist 1 Chemical Structure

CAS No.: 1283095-64-6

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

NOP antagonist 1 (Compound (-)-31) is a nociceptin opioid peptide (NOP) antagonist with a K_b of 8.65  nM. NOP antagonist 1 can be used for neuropsychiatric disorders research^[1].

IC₅₀ & Target^[1]

NOP

8.65 nM (Kb)

All Opioid Receptor Isoforms :

Chemical Information

CAS No. 1283095-64-6
Molecular Weight 406.49
Formula C₂₁H₂₄F₂N₂O₂S
SMILES

FC1=CC2=C(C3(OCC2)CCN(CC3)C[C@@H](C(N)=O)CC4=C(C=CC=C4)F)S1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pedregal C, et al. Development of LC-MS/MS-based receptor occupancy tracers and positron emission tomography radioligands for the nociceptin/orphanin FQ (NOP) receptor. J Med Chem. 2012 Jun 14;55(11):4955-67. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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NOP antagonist 1

All Opioid Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

NOP antagonist 1 Related Classifications

HY-176505 Related Classifications