Norspermine
Based on 1 Customer Validation
Norspermine is a synthetic tetraamine polyamine and a structural analog of Thermospermine (HY-151224), discovered in Thermodesulfobacterium thermophilum and Thermus thermophilus. Norspermine can partially substitute for Thermospermine function during growth and development, and is used in research on tumors, infections, and other conditions.
For research use only. We do not sell to patients.
- Purity : 99.94%
- CAS No.: 4605-14-5
- Formula: C9H24N4
- Molecular Weight:188.31
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 4605-14-5
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Appearance Liquid (Density: 0.931±0.06 g/cm3)
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Molecular Weight 188.31
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Formula C9H24N4
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Color Colorless to light yellow
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SMILES
NCCCNCCCNCCCN
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Structure Classification
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Initial Source
Rhodophyta
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 175 mg/mL (929.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
[1]. Li B, et al. Functional identification of bacterial spermine, thermospermine, norspermine, norspermidine, spermidine, and N-aminopropylagmatine synthases. The Journal of biological chemistry. 2024 May;300(5):107281. [Content Brief]
[2]. Perevoshchikova KA, et al. Symmetric lipophilic polyamines exhibiting antitumor activity. Bioorganic & medicinal chemistry. 2022 Dec 15;76:117089. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.3104 mL | 26.5520 mL | 53.1039 mL | 132.7598 mL |
| 5 mM | 1.0621 mL | 5.3104 mL | 10.6208 mL | 26.5520 mL | |
| 10 mM | 0.5310 mL | 2.6552 mL | 5.3104 mL | 13.2760 mL | |
| 15 mM | 0.3540 mL | 1.7701 mL | 3.5403 mL | 8.8507 mL | |
| 20 mM | 0.2655 mL | 1.3276 mL | 2.6552 mL | 6.6380 mL | |
| 25 mM | 0.2124 mL | 1.0621 mL | 2.1242 mL | 5.3104 mL | |
| 30 mM | 0.1770 mL | 0.8851 mL | 1.7701 mL | 4.4253 mL | |
| 40 mM | 0.1328 mL | 0.6638 mL | 1.3276 mL | 3.3190 mL | |
| 50 mM | 0.1062 mL | 0.5310 mL | 1.0621 mL | 2.6552 mL | |
| 60 mM | 0.0885 mL | 0.4425 mL | 0.8851 mL | 2.2127 mL | |
| 80 mM | 0.0664 mL | 0.3319 mL | 0.6638 mL | 1.6595 mL | |
| 100 mM | 0.0531 mL | 0.2655 mL | 0.5310 mL | 1.3276 mL |
Norspermine Related Classifications
HY-W090915 Related Classifications
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