1. Anti-infection
  2. Virus Protease
  3. NS2B/NS3-IN-6

NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively.

For research use only. We do not sell to patients.

NS2B/NS3-IN-6 Chemical Structure

NS2B/NS3-IN-6 Chemical Structure

CAS No. : 2459657-57-7

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Description

NS2B/NS3-IN-6 (Compound 1a) is an allosteric DENV and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively[1].

IC50 & Target

IC50: 2.23 µM (ZIKV NS2B/NS3 protease), 25.2 µM (DENV NS2B/NS3 protease)[1]

Molecular Weight

433.50

Formula

C19H19N3O5S2

CAS No.
SMILES

O=S(N1[C@@H](CCC1)C(NC2=NC3=CC(O)=C(O)C=C3S2)=O)(C4=CC=C(C=C4)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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NS2B/NS3-IN-6 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
NS2B/NS3-IN-6
Cat. No.:
HY-144742
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