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Cat. No.: HY-179567

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NVP-EGT710

(Synonyms: EGT710)

NVP-EGT710 (EGT710) is an orally active non-peptidomimetic covalent SARS-CoV-2 Mpro inhibitor. NVP-EGT710 can be used for coronavirus infection research.

For research use only. We do not sell to patients.

CAS No.: 2893895-11-7
Formula: C₁₉H₁₂F₃N₅O
Molecular Weight:383.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NVP-EGT710 Chemical Structure

CAS No.: 2893895-11-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

NVP-EGT710 (EGT710) is an orally active non-peptidomimetic covalent SARS-CoV-2 Mpro inhibitor. NVP-EGT710 can be used for coronavirus infection research^[1].

Chemical Information

CAS No. 2893895-11-7
Molecular Weight 383.33
Formula C₁₉H₁₂F₃N₅O
SMILES

N#C[C@H]1CN(C(N1C2=CN=CC3=C2C=CC=C3)=O)C4=CC=C(N=C4)C(F)(F)F
Synonyms

EGT710
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Matt Hesse. NVP-EGT710: Novartis’ Oral Covalent SARS-CoV-2 Mpro Inhibitor from Screen to Candidate in 18 Months. Oct. 29, 2025.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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