PX20606

(Synonyms: PX-102)

PX20606 is an orally active agonist for farnesoid X receptor (FXR), with EC50 220 nM (mFXR) and 50 nM (hFXR), measured by Gal4-FXR assay. PX20606 induces the expression of tumor suppressor gene NDRG2, inhibits the tumor growth and metastasis in mouse HCC model. PX20606 exhibits hepatoprotective efficacy.

For research use only. We do not sell to patients.

  • CAS No.: 1268245-19-7
  • Formula: C29H22Cl3NO4
  • Molecular Weight:554.85
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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