1 Result for "

ono-7475

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ono-7475" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-114358
CAS No.: 1646839-59-9
Purity:  98.59%
Synonyms: ono-7475
Research Areas:  

Cancer

Tamnorzatinib (ONO-7475) is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. Tamnorzatinib sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. Tamnorzatinib combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated non-small cell lung cancer (NSCLC).
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