Orphine
Based on 1 Customer Validation
Orphine is an opioid compound. Orphine can enhance the antinociceptive effects in mice that are mitigated by Naloxone (HY-17417).
For research use only. We do not sell to patients.
- Purity: 98.2%
- CAS No.: 59708-49-5
- Formula: C20H23N3O
- Molecular Weight:321.42
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Opioid Receptor Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 59708-49-5
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Appearance Solid
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Molecular Weight 321.42
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Formula C20H23N3O
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Color White to off-white
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SMILES
O=C1NC2=C(N1C3CCN(C(C)C4=CC=CC=C4)CC3)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 10 mg/mL (31.11 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Kennedy NM, et al. Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias. J Med Chem. 2018 Oct 11;61(19):8895-8907. [Content Brief]
[2]. Vandeputte MM, et al. Elucidating the harm potential of brorphine analogues as new synthetic opioids: Synthesis, in vitro, and in vivo characterization. Neuropharmacology. 2024 Dec 1;260:110113. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1112 mL | 15.5560 mL | 31.1119 mL | 77.7798 mL |
| 5 mM | 0.6222 mL | 3.1112 mL | 6.2224 mL | 15.5560 mL | |
| 10 mM | 0.3111 mL | 1.5556 mL | 3.1112 mL | 7.7780 mL | |
| 15 mM | 0.2074 mL | 1.0371 mL | 2.0741 mL | 5.1853 mL | |
| 20 mM | 0.1556 mL | 0.7778 mL | 1.5556 mL | 3.8890 mL | |
| 25 mM | 0.1244 mL | 0.6222 mL | 1.2445 mL | 3.1112 mL | |
| 30 mM | 0.1037 mL | 0.5185 mL | 1.0371 mL | 2.5927 mL |
Orphine Related Classifications
HY-168352 Related Classifications
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