P-gp inhibitor 28
P-gp inhibitor 28 (Compound 4h) is an inhibitor targeting P-glycoprotein (P-gp). It can inhibit the proliferation of cancer cells, and its IC50 value for MCF-7/ADR cells is between 15.88 and 21.96 μM. P-gp inhibitor 28 can increase the accumulation of Rho123 in MCF-7/ADR cells and can be used in research related to cancer and overcoming multidrug resistance in tumors.
For research use only. We do not sell to patients.
- Formula: C27H20N2O4
- Molecular Weight:436.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 436.46
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Formula C27H20N2O4
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SMILES
O=C1OC2=CC=C(C)C=C2C3=C1C(C4=CC=C(OCC5=CC=CC=C5)C=C4)C(C#N)=C(N)O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)