Peptide5

Cat. No.: HY-P2275: FAQs
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Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury

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Peptide5 Chemical Structure

CAS No. : 916977-43-0

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Other In-stock Forms of Peptide5:

Peptide5 TFA

Other Forms of Peptide5:

Peptide5 TFA In-stock

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Description	Peptide5, a connexin 43 mimetic peptide, reduce animals swelling, astrogliosis, and neuronal cell death after spinal cord injury^[1]
In Vitro	Peptide5, significantly reduces the degree of spinal cord injury (SCI) in a rodent ex vivo model. Peptide5 produces the more significant reduction in swelling and is analyzed further. Treatment with peptide5 reduced both the level of Cx43 and the number of glial fibrillary acidic protein (GFAP)-positive astrocytes, and at the same time reduces the loss of NeuN- and SMI-32–positive neurons in a concentration- and time-dependent manner^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Peptide5 Related Antibodies
In Vivo	Peptide5 is could be used to treat traumatic spinal cord injured rats^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight	1395.58
Formula	C₆₀H₉₈N₁₆O₂₀S
CAS No.	916977-43-0
Sequence Shortening	VDCFLSRPTEKT
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (258 KB) Handling Instructions (2659 KB)
References	[1]. Simon J O'Carroll, et al. Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury. Cell Commun Adhes. 2008 May;15(1):27-42. [Content Brief] [2]. Yilin Mao, et al. Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats. Exp Brain Res. 2017 Oct;235(10):3033-3048. [Content Brief]

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Peptide5916977-43-0Peptide 5Peptide-5Gap Junction ProteinInhibitorinhibitorinhibit

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Peptide5

Other Forms of Peptide5:

Peptide5 Related Antibodies

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Biological Activity

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