Phosphodiesterase l, Rattlesnake venom
Phosphodiesterase l, Rattlesnake venom (PDE, Rattlesnake venom) is a non-selective phosphodiester bond hydrolase targeting phosphodiester bonds in oligonucleotides, catalyzing their hydrolysis into mononucleotides. Phosphodiesterase l, Rattlesnake venom cleaves phosphodiester linkages in DNA fragments digested by DNase I. Phosphodiesterase l, Rattlesnake venom is promising for research of nucleic acid structure and metabolism.
For research use only. We do not sell to patients.
- CAS No.: 9025-82-5
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Phosphodiesterase l, Rattlesnake venom is a single-chain glycoprotein that sequentially hydrolyzes oligonucleotides from the 3'-hydroxyl end to release 5'-mononucleotides[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 9025-82-5
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SMILES
[Phosphodiesterase l, Rattlesnake venom]
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Synonyms
PDE, Rattlesnake venom
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Agarose gel electrophoresis (200 bp-5 kb)
Agarose gel electrophoresis is a molecular biology technique that uses agarose gel as a support medium to separate DNA fragments through a combination of molecular sieving and charge effects.
Purity & Documentation
References
[1]. Al-Saleh SS, et al. Purification and characterization of phosphodiesterase i from Walterinnesia aegyptia venom. Prep Biochem Biotechnol. 2011;41(3):262-277. [Content Brief]
[2]. PRIVAT DE GARILHE M, et al. Studies of the phosphodiesterase from rattlesnake venom. Biochim Biophys Acta. 1955 Nov;18(3):370-8. [Content Brief]
[3]. Uzair B, et al. Phosphodiesterases (PDEs) from Snake Venoms: Therapeutic Applications. Protein Pept Lett. 2018;25(7):612-618. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phosphodiesterase l, Rattlesnake venom Related Classifications
HY-P2878A Related Classifications
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