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Art. -Nr.: HY-189744

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PPO-IN-28

PPO-IN-28 is a protoporphyrinogen IX oxidase (PPO) inhibitor with a K_i of 15.6 nM against Nicotiana tabacum PPO. PPO-IN-28 binds to the PPO active site and blocks the catalytic conversion of protoporphyrinogen IX to protoporphyrin IX, leading to accumulation of protoporphyrinogen IX and reactive oxygen species-mediated membrane lipid peroxidation. PPO-IN-28 exhibits broad-spectrum post-emergence herbicidal activity against various weed species. PPO-IN-28 shows favorable crop safety in crops such as corn and wheat. PPO-IN-28 can be used in research related to plant herbicides.

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CAS. Nr.: 3127787-62-3
Formel: C₂₀H₁₈ClF₄N₃O₅
Molecular Weight:491.82

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

PPO-IN-28 Chemical Structure

CAS. Nr.: 3127787-62-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
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Biologische Aktivität

Beschreibung

In Vitro

PPO-IN-28 (Compound C34) (0.5 nM-50 mM) is a potent NtPPO inhibitor with K_i = 15.6 nM in cell-free enzyme assays^[1].
PPO-IN-28 (9.375-150 g a.i./ha) exhibits strong post-emergence herbicidal activity against six weeds, and completely inhibits P. oleracea and A. juncea even at low concentrations^[1].
PPO-IN-28 (75-150 g a.i./ha) exhibits broad-spectrum herbicidal activity and completely inhibits 17 weed species at high concentrations^[1].
PPO-IN-28 (75-150 g a.i./ha; 25 days) has good crop safety, causing 10-20% phytotoxicity to peanuts and soybeans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 3127787-62-3
Molecular Weight 491.82
Formel C₂₀H₁₈ClF₄N₃O₅
SMILES

CC1=CC(C(F)(F)F)=NN1C2=CC(C3=NOC(C(OC(C(OC)=O)C)=O)(C)C3)=C(Cl)C=C2F
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Zhang J, et al. Discovery of Novel N-Phenylpyrazole Derivatives as Protoporphyrinogen IX Oxidase Inhibitors[J]. Journal of Agricultural and Food Chemistry, 2026, 74(38): 29909-29919.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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