1. Epigenetics TGF-beta/Smad
  2. PKC
  3. Protein kinase inhibitor 9

Protein kinase inhibitor 9 (Compound example 175) is an inhibitor of serine/threonine and tyrosine kinase activity. Protein kinase inhibitor 9 can be used for the research of cancer, hyper proliferative disorders, rheumatoid arthritis, disorders of the immune system, transplant rejections and imflammatory disorders.

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Protein kinase inhibitor 9

Protein kinase inhibitor 9 Estructura química

No. CAS : 262433-52-3

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Descripciòn

Protein kinase inhibitor 9 (Compound example 175) is an inhibitor of serine/threonine and tyrosine kinase activity. Protein kinase inhibitor 9 can be used for the research of cancer, hyper proliferative disorders, rheumatoid arthritis, disorders of the immune system, transplant rejections and imflammatory disorders[1].

Peso molecular

398.46

Fòrmula

C24H22N4O2

No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1CCC(N2C=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(N)N=CN=C52)CC1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 20 mg/mL (50.19 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5097 mL 12.5483 mL 25.0966 mL
5 mM 0.5019 mL 2.5097 mL 5.0193 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5097 mL 12.5483 mL 25.0966 mL 62.7416 mL
5 mM 0.5019 mL 2.5097 mL 5.0193 mL 12.5483 mL
10 mM 0.2510 mL 1.2548 mL 2.5097 mL 6.2742 mL
15 mM 0.1673 mL 0.8366 mL 1.6731 mL 4.1828 mL
20 mM 0.1255 mL 0.6274 mL 1.2548 mL 3.1371 mL
25 mM 0.1004 mL 0.5019 mL 1.0039 mL 2.5097 mL
30 mM 0.0837 mL 0.4183 mL 0.8366 mL 2.0914 mL
40 mM 0.0627 mL 0.3137 mL 0.6274 mL 1.5685 mL
50 mM 0.0502 mL 0.2510 mL 0.5019 mL 1.2548 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Protein kinase inhibitor 9
Cat. No.:
HY-401475
Cantidad:
MCE Japan Authorized Agent: