Furanocoumarins from the root of Angelica dahurica

  • Arch Pharm Res. 2000 Oct;23(5):467-70. doi: 10.1007/BF02976574.
N I Baek  1 ,  E M Ahn ,  H Y Kim ,  Y D Park
Affiliations
  • 1. Department of Life Sciences and Institute of Life Sciences, Kyunghee University, Suwon, Korea. [email protected]
PMID: 11059825 DOI: 10.1007/BF02976574
Abstract

Five furanocoumarins including a new one were isolated from the root of Angelica dahurica by repeated silica gel column chromatography. Their chemical structures were determined to be isoimperatorin (1), oxypeucedanin hydrate-3"-butyl ether (2), imperatorin (3), knidilin (4), and oxypeucedanin hydrate (5). This represents the first study in which the compound 2 has been isolated and identified. The long-range coupling (5J) in the 1H-NMR spectrum observed in the linear furanocoumarin skeleton was also investigated in detail.

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