Cytotoxic oxoisoaporphine alkaloids from Menispermum dauricum

  • J Nat Prod. 2001 Jul;64(7):968-70. doi: 10.1021/np000532t.
B W Yu  1 ,  L H Meng ,  J Y Chen ,  T X Zhou ,  K F Cheng ,  J Ding ,  G W Qin
Affiliations
  • 1. Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, People's Republic of China.
PMID: 11473438 DOI: 10.1021/np000532t
Abstract

Four new oxoisoaporphine Alkaloids, daurioxoisoporphines A-D (1-4), were isolated from the rhizomes of Menispermum dauricum. The structures of these Alkaloids were established by spectroscopic methods. The cytotoxic evaluation of 1 and 2 is reported against four Cancer cell lines.