Matrix metalloproteinases: a tail of a frog that became a prince
- Nat Rev Mol Cell Biol. 2002 Mar;3(3):207-14. doi: 10.1038/nrm763.
Affiliations
- 1. Department of Medicine, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
PMID: 11994741
DOI: 10.1038/nrm763
Abstract
It is 40 years since the first member of what came to be known as the matrix metalloproteinase (MMP) family was described. Structural, molecular and biochemical approaches have subsequently contributed to piecing together the puzzle of how MMPs work, and how they contribute to various disease processes.