Comparative activities of the oxazolidinone AZD2563 and linezolid against selected recent North American isolates of Streptococcus pneumoniae

  • Antimicrob Agents Chemother. 2002 Sep;46(9):3094-5. doi: 10.1128/AAC.46.9.3094-3095.2002.
Sue E Baum  1 ,  Sharon A Crawford ,  M L McElmeel ,  Cynthia G Whitney ,  James H Jorgensen
Affiliations
  • 1. Infectious Disease Service of Brooke Army Medical Center, San Antonio, Texas, USA.
PMID: 12183281 DOI: 10.1128/AAC.46.9.3094-3095.2002
Abstract

The activity of AZD2563 against 250 highly resistant pneumococci and 267 drug-susceptible isolates was determined. The AZD2563 MICs for 50 and 90% of the strains tested were 1 and 2 micro g/ml and 0.5 and 1 micro g/ml, respectively, for the two isolate groups. These MICs were within 1 log(2) dilution of those of linezolid.

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