New A-ring lactone triterpenoid saponins from the roots of Platycodon grandiflorum

  • Chem Pharm Bull (Tokyo). 2006 Sep;54(9):1285-7. doi: 10.1248/cpb.54.1285.
Wen-Wei Fu  1 ,  Noriko Shimizu ,  Tadahiro Takeda ,  De-Qiang Dou ,  Baohui Chen ,  Yue-Hu Pei ,  Ying-Jie Chen
Affiliations
  • 1. Shenyang Pharmaceutical University, School of Traditional Chinese Material, 103 Wenhua Road, Shenhe District, Shenuang 110016, China.
PMID: 16946536 DOI: 10.1248/cpb.54.1285
Abstract

Three new A-ring lactone triterpenoid saponins, platycoside M-1 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone], platycoside M-2 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], and platycoside M-3 [3-O-beta-D-glucopyranosyl platycogenic acid A lactone 28-O-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], were isolated from the roots of Platycodon grandiflorum A. DC. Their chemical structures were elucidated on the basis of their spectral data and chemical evidence.

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