A concise total synthesis of melithiazole C

  • Org Lett. 2007 Aug 16;9(17):3425-7. doi: 10.1021/ol701459j.
Julian Gebauer  1 ,  Stellios Arseniyadis ,  Janine Cossy
Affiliations
  • 1. Laboratoire de Chimie Organique, ESPCI, CNRS, 10 rue Vauquelin, F-75231 Paris Cedex 05, France.
PMID: 17637033 DOI: 10.1021/ol701459j
Abstract

A short and convergent synthesis of the myxobacterial Antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.

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