Pregnane glycosides from Cynanchum atratum

  • Steroids. 2008 Jan;73(1):96-103. doi: 10.1016/j.steroids.2007.09.004.
Hong Bai  1 Wei Li Kazuo Koike
Affiliations
  • 1. Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Abstract

Five new pregnane glycosides, cynanosides K-O (1-5) with a 14,15-seco-pregnane-type skeleton as the aglycon, together with five known compounds, cynascyroside C, sublanceoside E(1), sublanceoside I(1), atratoside A and atratoside B, were isolated from the roots of Cynanchum atratum. Their structures were determined on the basis of spectroscopic analysis and chemical evidence.

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