Strong inhibition of cholera toxin binding by galactose dendrimers

  • Chem Commun (Camb). 2007 Dec 21;(47):5043-5. doi: 10.1039/b711070g.
Hilbert M Branderhorst  1 ,  Rob M J Liskamp ,  Gerben M Visser ,  Roland J Pieters
Affiliations
  • 1. Department of Medicinal Chemistry and Chemical Biology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, PO Box 80082, 3508 TB Utrecht, The Netherlands.
PMID: 18049747 DOI: 10.1039/b711070g
Abstract

Galactose-containing dendrimers with long spacer arms inhibit cholera toxin binding as strongly as the natural ganglioside GM1 oligosaccharide does.

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