Aminocaprophenone- and pyrrolidine-type alkaloids from the leaves of Ficus septica

  • J Nat Prod. 2009 Dec;72(12):2181-3. doi: 10.1021/np900580f.
Jun-ya Ueda  1 ,  Motoki Takagi ,  Kazuo Shin-ya
Affiliations
  • 1. Biomedicinal Information Research Center, Japan Biological Informatics Consortium, 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan.
PMID: 19938815 DOI: 10.1021/np900580f
Abstract

Two new aminocaprophenone Alkaloids, ficuseptamines A (1) and B (2), and a new pyrrolidine alkaloid, ficuseptamine C (3), together with 12 known Alkaloids and a known acetophenone derivative were isolated from a methanolic extract of the leaves of Ficus septica. The structures of 1-3 were determined on the basis of their spectroscopic data. The compounds obtained were evaluated for cytotoxicity against two Cancer cell lines.