Effect of pirazolac on prostanoid synthesis by human gastric mucosa in vitro

  • Drugs Exp Clin Res. 1990;16(1):1-6.
I A Tavares  1 ,  A Bennett
Affiliations
  • 1. Department of Surgery, King's College School of Medicine and Dentistry, Rayne Institute, London, UK.
PMID: 2115830
Abstract

Pirazolac concentration-relatedly inhibited the accumulation of prostanoids in incubates of human gastric mucosa, but this inhibition was less than that by indomethacin and Other commonly used non-steroidal anti-inflammatory drugs. This difference may explain the claim that pirazolac is less damaging to the stomach.

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