Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies

  • J Med Chem. 2012 May 24;55(10):4539-50. doi: 10.1021/jm300035p.
Yan Lou  1 ,  Timothy D Owens ,  Andreas Kuglstatter ,  Rama K Kondru ,  David M Goldstein
Affiliations
  • 1. Discovery Chemistry, Small Molecule Research, pRED, Pharma Research and Early Development, Hoffmann-La Roche Inc. , 340 Kingsland Street, Nutley, New Jersey 07110, United States. [email protected]
PMID: 22394077 DOI: 10.1021/jm300035p