A new triterpene saponin from the roots of Ilex pubescens

  • Nat Prod Res. 2013 Aug;27(15):1343-7. doi: 10.1080/14786419.2012.738208.
Zhong-Liu Zhou  1 ,  Zong-Cai Feng ,  Chun-Yan Fu ,  Li Zeng
Affiliations
  • 1. Chemistry Science and Technology School, Zhanjiang Normal University, 29 Cunjin Road, Zhanjiang 524048, P.R. China. [email protected]
PMID: 23092447 DOI: 10.1080/14786419.2012.738208
Abstract

A new triterpene saponin, ilexoside P (1), along with three known triterpene saponins, ilexoside O (2), ilexsaponin B3 (3) and ilexpublesnin A (4) was isolated from the roots of Ilex pubescens. Their chemical structures were elucidated on the basis of UV, IR, MS, and NMR spectroscopic analyses coupled with chemical degradation. In addition, the Xanthine Oxidase (XOD) inhibitory activity of the isolated saponins was reported. Compound 1 exhibited weak XOD inhibitory activity in the test.

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