New triterpene glycosides from Ziziphi Spinosae Semen

  • Fitoterapia. 2013 Oct;90:185-91. doi: 10.1016/j.fitote.2013.07.013.
Yu Wang  1 ,  Bo Ding ,  Dan Luo ,  Liu-Yuan Chen ,  Yun-Long Hou ,  Yi Dai ,  Xin-Sheng Yao
Affiliations
  • 1. College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.
PMID: 23912064 DOI: 10.1016/j.fitote.2013.07.013
Abstract

Four new dammarane-type triterpene glycosides, named jujubosides I-IV (1-4), were isolated from Ziziphi Spinosae Semen, along with seven known saponins (5-11). The structures of new compounds were established on the basis of extensive spectroscopic analysis. All compounds were evaluated for the effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide in vitro.

Keywords
Chemical components; Myocardial injury; Triterpenoid saponins; Ziziphi Spinosae Semen.
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