In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria

  • Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92. doi: 10.1128/AAC.01509-13.
Y López  1 ,  M Tato ,  P Espinal ,  F Garcia-Alonso ,  D Gargallo-Viola ,  R Cantón ,  J Vila
Affiliations
  • 1. Barcelona Centre for International Health Research (CRESIB), Barcelona, Spain.
PMID: 24080666 DOI: 10.1128/AAC.01509-13
Abstract

In vitro activity of ozenoxacin, a novel nonfluorinated topical (L. D. Saravolatz and J. Leggett, Clin. Infect. Dis. 37:1210-1215, 2003) Quinolone, was compared with the activities of Other quinolones against well-characterized quinolone-susceptible and quinolone-resistant Gram-positive bacteria. Ozenoxacin was 3-fold to 321-fold more active than Other quinolones. Ozenoxacin could represent a first-in-class nonfluorinated Quinolone for the topical treatment of a broad range of dermatological infections.

Products