Identification of ML359 as a Small Molecule Inhibitor of Protein Disulfide Isomerase

Carol Khodier  1 ,  Lynn VerPlank  1 ,  Partha P. Nag  1 ,  Jun Pu  1 ,  Jacqueline Wurst  1 ,  Tatiana Pilyugina  1 ,  Chris Dockendorff  1 ,  Christine N. Galinski  2 ,  Alissa A. Scalise  2 ,  Freda Passam  3 ,  Lotte van Hessem  4 ,  James Dilks  4 ,  Daniel R. Kennedy  2 ,  Robert Flaumenhaft  4 ,  Michelle A. J. Palmer  1 ,  Sivaraman Dandapani  1 ,  Benito Munoz  1 ,  Stuart L. Schrieber  1  5  6
Affiliations
  • 1. The Broad Institute Probe Development Center, Cambridge, MA
  • 2. College of Pharmacy, Western New England University, Springfield, MA
  • 3. St. George Clinical School, University of New South Wales, Sydney, Australia
  • 4. Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
  • 5. Chemical Biology Program, Broad Institute, Cambridge, MA
  • 6. Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA
PMID: 24624466
Products