Additional new minor cucurbitane glycosides from Siraitia grosvenorii

  • Molecules. 2014 Mar 24;19(3):3669-80. doi: 10.3390/molecules19033669.
Indra Prakash  1 Venkata Sai Prakash Chaturvedula  2
Affiliations
  • 1. The Coca-Cola Company, Organic Chemistry Department, Global Research and Development, One Coca-Cola Plaza, Atlanta, GA 30313, USA. [email protected].
  • 2. Natural Ingredient Development, Blue California, 30111 Tomas, Rancho Santa Margarita, CA 92688, USA. [email protected].
Abstract

Continuous phytochemical studies of the crude extract of Luo Han Guo (Siraitia grosvenorii) furnished three additional new cucurbitane triterpene glycosides, namely 11-deoxymogroside V, 11-deoxyisomogroside V, and 11-deoxymogroside VI. The structures of all the isolated compounds were characterized on the basis of extensive NMR and mass spectral data as well as hydrolysis studies. The complete ¹H- and ¹³C-NMR spectral assignments of the three unknown compounds are reported for the first time based on COSY, TOCSY, HSQC, and HMBC spectroscopic data.

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