Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1

Ganesha Rai  1 ,  Netra Joshi  2 ,  Steve Perry  2 ,  Adam Yasgar  1 ,  Lena Schultz  1 ,  Jog Eun Jung  3 ,  Yu Liu  3 ,  Yasukazu Terasaki  3 ,  Giovanni Diaz  2 ,  Victor Kenyon  2 ,  Ajit Jadhav  1 ,  Anton Simeonov  1 ,  Klaus van Leyen  3 ,  Theodore R. Holman  2 ,  David J. Maloney  1
Affiliations
  • 1. National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD
  • 2. Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA
  • 3. Neuroprotection Research Laboratory, Massachusetts General Hospital, Charlestown, MA
PMID: 24672829
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