Two new avermectin derivatives from the Beibu Gulf gorgonian Anthogorgia caerulea

  • Chem Biodivers. 2014 May;11(5):812-8. doi: 10.1002/cbdv.201300265.
Chenghai Gao  1 ,  Yibing Wang ,  Yinning Chen ,  Bijuan He ,  Rongcan Zhang ,  Mingben Xu ,  Riming Huang
Affiliations
  • 1. Guangxi Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning 53007, P. R. China.
PMID: 24827692 DOI: 10.1002/cbdv.201300265
Abstract

Two new avermectin derivatives, avermectins B1c and B1e (1 and 2, resp.), as well as two known compounds, avermectin B2a (3) and ivermectin A1a (4), were isolated from a Beibu Gulf gorgonian coral, Anthogorgia caerulea. The structures of the new compounds were established by detailed spectroscopic analysis and by comparison with spectral data of related known compounds. Compounds 1-4 showed moderate antifouling activities against the larval settlement of Balanus amphitrite.

Keywords
Anthogorgia caerulea; Antifouling activity; Avermectins B1c and B1e.
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