Antibiotics from basidiomycetes. XXXI. Aleurodiscal: an antifungal sesterterpenoid from Aleurodiscus mirabilis (Berk. & Curt.) Höhn

  • J Antibiot (Tokyo). 1989 Jun;42(6):875-82. doi: 10.7164/antibiotics.42.875.
U Lauer  1 ,  T Anke ,  W S Sheldrick ,  A Scherer ,  W Steglich
Affiliations
  • 1. Lehrbereich Biotechnologie der Universität, Kaiserslautern, FRG.
PMID: 2500412 DOI: 10.7164/antibiotics.42.875
Abstract

Aleurodiscal, an antifungal Antibiotic has been isolated from mycelial cultures of Aleurodiscus mirabilis (Berk. & Curt.) Höhn. It causes abnormal apical branchings of Mucor miehei hyphae at very low concentrations. The structure and absolute configuration of the Antibiotic has been determined by a single crystal X-ray analysis and hydrolysis to D-(+)-xylose. Aleurodiscal is a hydroxysesterterpene aldehyde beta-D-xyloside with a novel carbon skeleton.

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