An antitumor principle from Euphorbia lathyris

  • Planta Med. 1989 Jun;55(3):271-2. doi: 10.1055/s-2006-962001.
H Itokawa ,  Y Ichihara ,  K Watanabe ,  K Takeya
PMID: 2740459 DOI: 10.1055/s-2006-962001
Abstract

The extract of seeds of Euphorbia lathyris L. showed antitumor activity against Sarcoma 180 ascites in mice. Systematic fractionation of the extract led to the characterization of ingenol-3-hexadecanoate as an active principle, together with an inactive diterpene ingenol-20-hexadecanoate.

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