Drychampones A-C: Three Meroterpenoids from Dryopteris championii
- J Org Chem. 2016 Oct 7;81(19):9443-9448. doi: 10.1021/acs.joc.6b01720.
Affiliations
- 1. Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632, People's Republic of China.
PMID: 27583635
DOI: 10.1021/acs.joc.6b01720
Abstract
Three novel sesquiterpenoid-based meroterpenoids, drychampones A-C (1-3, respectively), were isolated from Dryopteris championii. Compounds 1 and 3 possessed a novel carbon skeleton which was constructed by an 11/6/6 ring system coupled with a pyronone moiety, and 1-3 were three racemates. Their structures and absolute configurations were elucidated by NMR, MS, and computational methods. The hypothetical biosynthetic pathways of these meroterpenoids and their Antibacterial activities were also discussed.
Products
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Cat. No.Product NameDescriptionTargetResearch Area
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Research Areas: Cancer