(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer

  • Biol Proced Online. 2025 Dec 5. doi: 10.1186/s12575-025-00312-2.
Zhen-Yu Zhao  #  1 ,  Jian-Chun Wu  #  1 ,  Ying-Bin Luo  1 ,  Yu-Li Wang  1 ,  Xi Wang  1 ,  Jian-Hui Tian  1 ,  Bo Zhang  2 ,  Yan Li  3
Affiliations
  • 1. Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China.
  • 2. Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. [email protected].
  • 3. Clinical Medical Center of Oncology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China. [email protected].
  • # Contributed equally.
PMID: 41350836 DOI: 10.1186/s12575-025-00312-2
Keywords
(-)-Guaiol; CD36; CPT1; Lewis lung cancer; PPAR-γ.
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