Bioactive saponins and glycosides. X. On the constituents of zizyphi spinosi semen, the seeds of Zizyphus jujuba Mill. var. spinosa Hu (1): structures and histamine release-inhibitory effect of jujubosides A1 and C and acetyljujuboside B

  • Chem Pharm Bull (Tokyo). 1997 Jul;45(7):1186-92. doi: 10.1248/cpb.45.1186.
M Yoshikawa  1 ,  T Murakami ,  A Ikebata ,  S Wakao ,  N Murakami ,  H Matsuda ,  J Yamahara
Affiliations
  • 1. Kyoto Pharmaceutical University, Japan.
PMID: 9246753 DOI: 10.1248/cpb.45.1186
Abstract

New dammarane-type triterpene oligoglycosides, jujubosides A1 and C and acetyljujuboside B1 were isolated from Zizyphi Spinosi Semen, the seeds of Zizyphus jujuba MILL. var. spinosa Hu, together-with three known saponins. The structures of jujubosides A1 and C and acetyljujuboside B were determined on the basis of chemical and physicochemical evidence. Jujubosides A1 and C and acetyljujuboside B were found to inhibit the histamine release from rat peritoneal exudate cells induced by antigen-antibody-reaction.

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