From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

C K Lau  ¹ ,  W C Black ,  M Belley ,  C Chan ,  S Charleson ,  D Denis ,  J Y Gauthier ,  R Gordon ,  D Guay ,  P Hamel ,  S Kargman ,  Y Leblanc ,  J Mancini ,  M Ouellet ,  D Percival ,  P Prasit ,  P Roy ,  K Skorey ,  P Tagari ,  P Vickers ,  E Wong