L 748780
L 748780 (compound 2) is a selectivity COX-2 inhibitor with the IC50 values of 0.5 μM and > 100 μM for COX-2 and COX-1, respectively.
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- CAS. Nr.: 168086-64-4
- Formel: C19H14Cl3NO4
- Molecular Weight:426.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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COX-2 0.5 μM (IC50) |
COX-1 > 100 μM (IC50) |
Chemical Information
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CAS. Nr. 168086-64-4
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Molecular Weight 426.68
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Formel C19H14Cl3NO4
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SMILES
O=C(CC1=C(C)N(C(C2=C(Cl)C=C(Cl)C=C2Cl)=O)C3=C1C=C(C=C3)OC)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)