Three new manzamine congeners from amphimedon sponge

  • J Nat Prod. 1998 May;61(5):689-92. doi: 10.1021/np970564p.
D Watanabe  1 ,  M Tsuda ,  J Kobayashi
Affiliations
  • 1. Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
PMID: 9599281 DOI: 10.1021/np970564p
Abstract

Three new manzamine congeners (1-3) have been isolated from the Okinawan marine Sponge Amphimedon sp., and the structures, including relative stereochemistries, were elucidated on the basis of spectroscopic data. Absolute configuration at C-16 of 1 was determined by modified Mosher's method.