Puxitatug samrotecan drug-linker
Based on 1 Customer Validation
Puxitatug samrotecan drug-linker (AZD8205 drug-linker) is a drug-linker conjugate for ADC, which comprises a topoisomerase I inhibitor and a linker. Puxitatug samrotecan drug-linker can be used to synthesis antibody-drug conjugate (ADC), Puxitatug samrotecan (HY-171689).
For research use only. We do not sell to patients.
- Purity: 98.98%
- CAS No.: 3025787-81-6
- Formula: C60H84N8O20S
- Molecular Weight:1269.42
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3025787-81-6
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Appearance Solid
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Molecular Weight 1269.42
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Formula C60H84N8O20S
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Color Off-white to light yellow
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SMILES
O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(C(CC6=O)SC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=CC7=C1COC([C@]7(O)CC)=O
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Synonyms
AZD8205 drug-linker
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (78.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7878 mL | 3.9388 mL | 7.8776 mL | 19.6940 mL |
| 5 mM | 0.1576 mL | 0.7878 mL | 1.5755 mL | 3.9388 mL | |
| 10 mM | 0.0788 mL | 0.3939 mL | 0.7878 mL | 1.9694 mL | |
| 15 mM | 0.0525 mL | 0.2626 mL | 0.5252 mL | 1.3129 mL | |
| 20 mM | 0.0394 mL | 0.1969 mL | 0.3939 mL | 0.9847 mL | |
| 25 mM | 0.0315 mL | 0.1576 mL | 0.3151 mL | 0.7878 mL | |
| 30 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6565 mL | |
| 40 mM | 0.0197 mL | 0.0985 mL | 0.1969 mL | 0.4924 mL | |
| 50 mM | 0.0158 mL | 0.0788 mL | 0.1576 mL | 0.3939 mL | |
| 60 mM | 0.0131 mL | 0.0656 mL | 0.1313 mL | 0.3282 mL |
Puxitatug samrotecan drug-linker Related Classifications
HY-163487 Related Classifications
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