(±)-WB 4101
(±)-WB 4101 is a highly selective α1-adrenergic receptor antagonist. (±)-WB 4101 blocks norepinephrine-induced vascular smooth muscle contraction to exert antihypertensive and benign prostatic hyperplasia (BPH)-relieving effects. (±)-WB 4101 is promising for research of hypertension and BPH.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 613-67-2
- Formel: C19H23NO5
- Molecular Weight:345.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Alle Adrenergic Receptor Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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α1-adrenergic receptor |
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Cell Line
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Type | Value | Description | References |
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| CHO-K1 | IC50 |
1 nM
Compound: WB 4101
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Antagonist activity against human recombinant alpha1 receptor expressed in CHOK1 cells assessed as reduction in epinephrine-induced increase in intracellular Ca2+ levels
Antagonist activity against human recombinant alpha1 receptor expressed in CHOK1 cells assessed as reduction in epinephrine-induced increase in intracellular Ca2+ levels
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[PMID: 25557493] |
Chemical Information
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CAS. Nr. 613-67-2
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Molecular Weight 345.39
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Formel C19H23NO5
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SMILES
COC1=C(OCCNCC2OC3=CC=CC=C3OC2)C(OC)=CC=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(±)-WB 4101 Related Classifications
HY-12718 Related Classifications
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