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Cat. No.: HY-W704289

Raloxifene impurity 6

Raloxifene impurity 6 is an impurity of Raloxifene.

For research use only. We do not sell to patients.

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Please store the product under the recommended conditions in the Certificate of Analysis.

CAS No.: 185416-01-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Raloxifene impurity 6 is an impurity of Raloxifene.

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	190 nM Compound: 66b	Inhibition of 17beta-estradiol-induced human MCF7 cells proliferation assessed as reduction in [3H]thymidine incorporation preincubated for 48 hrs followed by [3H]thymidine addition measured after 4 hrs by liquid scintillation counting method Inhibition of 17beta-estradiol-induced human MCF7 cells proliferation assessed as reduction in [3H]thymidine incorporation preincubated for 48 hrs followed by [3H]thymidine addition measured after 4 hrs by liquid scintillation counting method	[PMID: 28759875]
MCF7	IC₅₀	190 nM Compound: 9b	Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-estradiol (in vitro) Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-estradiol (in vitro)	[PMID: 9003514]

CAS No. 185416-01-7
Molecular Weight 473.59
Formula C₂₈H₂₇NO₄S
SMILES

O=C(C1=CC=C(OCCN2CCCCC2)C=C1)C3=C(SC=4C=CC=C(O)C43)C=5C=CC(O)=CC5
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.