Raloxifene impurity 6
Raloxifene impurity 6 is an impurity of Raloxifene.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 185416-01-7
- Fòrmula: C28H27NO4S
- Peso molecular:473.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
190 nM
Compound: 66b
|
Inhibition of 17beta-estradiol-induced human MCF7 cells proliferation assessed as reduction in [3H]thymidine incorporation preincubated for 48 hrs followed by [3H]thymidine addition measured after 4 hrs by liquid scintillation counting method
Inhibition of 17beta-estradiol-induced human MCF7 cells proliferation assessed as reduction in [3H]thymidine incorporation preincubated for 48 hrs followed by [3H]thymidine addition measured after 4 hrs by liquid scintillation counting method
|
[PMID: 28759875] |
| MCF7 | IC50 |
190 nM
Compound: 9b
|
Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-estradiol (in vitro)
Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-estradiol (in vitro)
|
[PMID: 9003514] |
Chemical Information
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No. CAS 185416-01-7
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Peso molecular 473.59
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Fòrmula C28H27NO4S
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SMILES
O=C(C1=CC=C(OCCN2CCCCC2)C=C1)C3=C(SC=4C=CC=C(O)C43)C=5C=CC(O)=CC5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)