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Cat. No.: HY-116556

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Rilmakalim

(Synonyms: HOE 234)

Rilmakalim (HOE 234) is a potassium channel opener (PCO) that activates ATP-sensitive K⁺ channels in the heart or other tissues.

For research use only. We do not sell to patients.

CAS No.: 132014-21-2
Formula: C₂₁H₂₃NO₅S
Molecular Weight:401.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Rilmakalim Chemical Structure

CAS No.: 132014-21-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Rilmakalim (HOE 234) is a potassium channel opener (PCO) that activates ATP-sensitive K⁺ channels in the heart or other tissues^[1].

Chemical Information

CAS No. 132014-21-2
Molecular Weight 401.48
Formula C₂₁H₂₃NO₅S
SMILES

O=C1N(CCC1)[C@H]2[C@@H](C(C)(OC3=C2C=C(C=C3)S(=O)(C4=CC=CC=C4)=O)C)O
Synonyms

HOE 234
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kocic, Ivan et al. Hypotonic stress increases efficacy of rilmakalim, but not pinacidil, to activate ATP-sensitive K(+) current in guinea pig ventricular myocytes. Journal of pharmacological sciences vol. 95,2 (2004): 189-95. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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